12th International Conference on Food Chemistry and Food Microbiology
ICAR-Central Institute of Fisheries Education, India
Title: Edible antibodies (IgY) in health management
Biography: K Pani Prasad
Although, aquaculture has developed significantly, management of diseases needs more emphasis. Specific antibodies for designing and use of different immunodiagnostics are necessary. Secondly, there is a great scope for integration of passive immunization i.e. IgY immunotherapy, the concept in health management needs to be tapped. Specific antibodies produced in chickens offer several important advantages over producing antibodies in other mammals. A single egg contains as much antibody as an average 20 ml bleed from a rabbit. This simple, non-invasive approach presents an appealing alternative to conventional polyclonal antibodies production methods. In addition, the eggs from immunized chickens provide a continual, daily source of antibody and this convenient approach offers greater compatibility with animal protection regulations. These IgY antibodies could be used for either developing immunodiagnostic kits or in passive immunotherapy against diseases. The IgY antibodies are stable in the intestinal tract of humans and animals and many reports are available. These antibodies are used in the prevention of many bacterial and viral diseases viz. gingivitis, dental caries, gastritis, gastric ulcers, infant rotavirus diarrhea in humans; livestock diseases such as mastitis and diarrhea, poultry diseases such as Salmonella, Campylobacteriosis, infectious bursal disease and Newcastle disease; as well as aquatic diseases like shrimp white spot syndrome virus, Yersinia ruckeri and Edwardsiella tarda. The positive results have led to penetrate the market of novel nutraceuticals and health supplements. This will reduce the use of chemicals/antibiotics, etc. in the environment and also help in controlling infections. With the use of these natural products of IgY, there would be increased use of these functional foods in the treatment and control of diseases at a reduced cost with no side effects to the body.